| 1 | SUPN | Supernus Pharmaceuticals, Inc. | 4.94% |
| 2 | XENE | Xenon Pharmaceuticals Inc. | 4.73% |
| 3 | ACAD | ACADIA Pharmaceuticals Inc. | 4.40% |
| 4 | ARGX | argenx SE | 4.40% |
| 5 | KRX: 326030 | SK Biopharmaceuticals Co., Ltd. | 4.32% |
| 6 | NBIX | Neurocrine Biosciences, Inc. | 4.13% |
| 7 | BIIB | Biogen Inc. | 4.00% |
| 8 | DNLI | Denali Therapeutics Inc. | 3.88% |
| 9 | SRRK | Scholar Rock Holding Corporation | 3.73% |
| 10 | PTCT | PTC Therapeutics, Inc. | 3.70% |
| 11 | HLUNB.CO | H. LUNDBECK CLASS B | 3.59% |
| 12 | ALKS | Alkermes plc | 3.52% |
| 13 | CPRX | Catalyst Pharmaceuticals, Inc. | 3.07% |
| 14 | BHVN | Biohaven Ltd. | 2.80% |
| 15 | STO: DYVOX | Dynavox Group AB (publ) | 2.73% |
| 16 | AVDL | Avadel Pharmaceuticals plc | 2.64% |
| 17 | ASX: NEU | Neuren Pharmaceuticals Limited | 2.60% |
| 18 | EWTX | Edgewise Therapeutics, Inc. | 2.37% |
| 19 | DYN | Dyne Therapeutics, Inc. | 2.35% |
| 20 | TYO: 4592 | SanBio Company Limited | 2.18% |
| 21 | STO: BIOA.B | BioArctic AB (publ) | 2.17% |
| 22 | IART | Integra LifeSciences Holdings Corporation | 1.97% |
| 23 | PRAX | Praxis Precision Medicines, Inc. | 1.92% |
| 24 | SRPT | Sarepta Therapeutics, Inc. | 1.86% |
| 25 | AVXL | Anavex Life Sciences Corp. | 1.84% |
| View IBRN holdings |