| 1 | ALNY | Alnylam Pharmaceuticals, Inc. | 7.25% |
| 2 | ILMN | Illumina, Inc. | 5.77% |
| 3 | GILD | Gilead Sciences, Inc. | 5.38% |
| 4 | RPRX | Royalty Pharma plc | 5.37% |
| 5 | AMGN | Amgen Inc. | 4.99% |
| 6 | BMRN | BioMarin Pharmaceutical Inc. | 4.79% |
| 7 | UTHR | United Therapeutics Corporation | 4.68% |
| 8 | VRTX | Vertex Pharmaceuticals Incorporated | 4.25% |
| 9 | AVXL | Anavex Life Sciences Corp. | 3.90% |
| 10 | COLL | Collegium Pharmaceutical, Inc. | 3.43% |
| 11 | INCY | Incyte Corporation | 3.33% |
| 12 | HALO | Halozyme Therapeutics, Inc. | 3.14% |
| 13 | PTGX | Protagonist Therapeutics, Inc. | 3.13% |
| 14 | ARWR | Arrowhead Pharmaceuticals, Inc. | 3.09% |
| 15 | ACAD | ACADIA Pharmaceuticals Inc. | 3.06% |
| 16 | FOLD | Amicus Therapeutics, Inc. | 2.98% |
| 17 | QGEN | Qiagen N.V. | 2.98% |
| 18 | DVAX | Dynavax Technologies Corporation | 2.89% |
| 19 | NBIX | Neurocrine Biosciences, Inc. | 2.80% |
| 20 | VCYT | Veracyte, Inc. | 2.74% |
| 21 | RGEN | Repligen Corporation | 2.64% |
| 22 | PTCT | PTC Therapeutics, Inc. | 2.52% |
| 23 | EXEL | Exelixis, Inc. | 2.35% |
| 24 | MNKD | MannKind Corporation | 2.32% |
| 25 | CPRX | Catalyst Pharmaceuticals, Inc. | 2.18% |
| View PBE holdings |