ALPS Medical Breakthroughs ETF (SBIO)

NYSEARCA: SBIO · Real-Time Price · USD
50.45
+0.30 (0.60%)
Dec 5, 2025, 4:00 PM EST - Market closed
0.60%
Assets $99.98M
Expense Ratio 0.50%
PE Ratio n/a
Shares Out 2.10M
Dividend (ttm) $1.17
Dividend Yield 2.33%
Ex-Dividend Date Dec 19, 2024
Payout Ratio n/a
1-Year Return +30.88%
Volume 31,905
Open 50.38
Previous Close 50.15
Day's Range 50.13 - 50.61
52-Week Low 22.33
52-Week High 50.61
Beta 0.80
Holdings 102
Inception Date Dec 31, 2014

About SBIO

Fund Home Page

The ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is issued by SS&C.

Asset Class Equity
Category Health
Region North America
Stock Exchange NYSEARCA
Ticker Symbol SBIO
ETF Provider SS&C
Index Tracked S-Network Medical Breakthroughs Index

Top 10 Holdings

31.20% of assets
Name Symbol Weight
Avidity Biosciences, Inc. RNA 4.44%
Arrowhead Pharmaceuticals, Inc. ARWR 3.71%
Cytokinetics, Incorporated CYTK 3.31%
Axsome Therapeutics, Inc. AXSM 3.18%
Rhythm Pharmaceuticals, Inc. RYTM 3.06%
Merus N.V. MRUS 2.99%
Nuvalent, Inc. NUVL 2.90%
Krystal Biotech, Inc. KRYS 2.61%
PTC Therapeutics, Inc. PTCT 2.53%
Vaxcyte, Inc. PCVX 2.47%
View More Holdings

Dividends

Ex-Dividend Amount Pay Date
Dec 19, 2024 $1.17346 Dec 26, 2024
Dec 21, 2023 $0.07106 Dec 27, 2023
Dec 19, 2019 $0.01585 Dec 27, 2019
Dec 20, 2018 $0.7841 Dec 27, 2018
Dec 21, 2017 $0.57949 Dec 28, 2017
Full Dividend History

News

SBIO: A Shock Biotech Winner In 2025

The ALPS Medical Breakthroughs ETF has staged a remarkable comeback, outperforming despite a challenging macro backdrop and small-cap weakness. SBIO benefited from a rebound in FDA drug approvals, pos...

7 days ago - Seeking Alpha

Sabio Holdings Inc. (SBIO:CA) Q3 2025 Earnings Call Transcript

Sabio Holdings Inc. ( SBIO:CA) Q3 2025 Earnings Call November 25, 2025 10:00 AM EST Company Participants Aziz Rahimtoola - Co-Founder, CEO & Chairman Sajid Premji - Chief Financial Officer Conference...

10 days ago - Seeking Alpha

Biotech Consolidation Could Perk Up, Lift This ETF

Regarding the healthcare sector again disappointing investors in 2025 — the largest ETF addressing the group is up just 11.39% — there are pockets of strength. Those include biotech stocks and the rel...

16 days ago - ETF Trends

Investing In Health Stocks - How Policy Clarity Is Opening Doors

The healthcare sector has experienced one of its most significant de-ratings in 35 years, with valuations now at a 30% discount to the broader market. Healthcare trades at historical valuation discoun...

24 days ago - Seeking Alpha

Healthcare Sector Checkup As U.S. Looks To Change Regulations

Outlook for pharma sector as Trump pushes for regulatory changes. The impact of tariffs on drugmakers.

6 months ago - Seeking Alpha

Seeking Stocks With Vitality In The Volatile Healthcare Sector

Investors cooled to the healthcare sector in 2024, which dramatically trailed global and US equity markets for the year. any investors are now asking: how will the policy changes under a new US admini...

10 months ago - Seeking Alpha

SBIO ETF: Betting On Medical Breakthroughs

ALPS Medical Breakthroughs ETF is rated Hold due to high fees, low yield, and mixed performance compared to other healthcare ETFs. The SBIO ETF focuses on small and mid-cap biotech companies with drug...

1 year ago - Seeking Alpha

Advacam & Vector Space Biosciences sign Letter of Intent (LOI) to Develop AI Models & CubeSat Payloads for the Space Industry

LA JOLLA, Calif.--(BUSINESS WIRE)---- $SBIO #Advacam--Advacam, provider of radiation detectors that map radiation aboard the International Space Station (ISS) and Vector Space Biosciences (crypto symb...

1 year ago - Business Wire

Vector Space Biosciences (SBIO) Is Now Available for Trading on LBank Exchange

Road Town, Virgin Islands--(Newsfile Corp. - September 24, 2023) - LBank Exchange, a global digital asset trading platform, listed Vector Space Biosciences (SBIO) on September 15, 2023. For all users ...

2 years ago - Newsfile Corp

Can Health Care Stocks Outperform Again In 2023?

How a recession could impact health care stocks in 2023. As Covid continues, what it could mean for the health care sector.

3 years ago - Seeking Alpha