ALPS Medical Breakthroughs ETF (SBIO)

SBIO Holdings List

As of May 12, 2025

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No.	Symbol	Name	% Weight	Shares
1	VRNA	Verona Pharma plc	5.01%	59,430
2	ALKS	Alkermes plc	4.45%	114,014
3	AXSM	Axsome Therapeutics, Inc.	4.38%	31,800
4	RYTM	Rhythm Pharmaceuticals, Inc.	3.36%	45,601
5	PTCT	PTC Therapeutics, Inc.	3.25%	56,568
6	RNA	Avidity Biosciences, Inc.	3.16%	86,140
7	AKRO	Akero Therapeutics, Inc.	2.97%	57,289
8	ZLAB	Zai Lab Limited	2.76%	75,268
9	CRNX	Crinetics Pharmaceuticals, Inc.	2.76%	66,329
10	MRUS	Merus N.V.	2.67%	50,330
11	ACAD	ACADIA Pharmaceuticals Inc.	2.57%	117,453
12	PTGX	Protagonist Therapeutics, Inc.	2.57%	45,391
13	XENE	Xenon Pharmaceuticals Inc.	2.44%	54,568
14	MLTX	MoonLake Immunotherapeutics	2.33%	46,479
15	DNLI	Denali Therapeutics Inc.	2.02%	109,433
16	MIRM	Mirum Pharmaceuticals, Inc.	1.99%	34,998
17	BCRX	BioCryst Pharmaceuticals, Inc.	1.94%	150,317
18	VCEL	Vericel Corporation	1.90%	35,691
19	NAMS	NewAmsterdam Pharma Company N.V.	1.84%	76,603
20	CGON	CG Oncology, Inc.	1.75%	55,615
21	FOLD	Amicus Therapeutics, Inc.	1.70%	218,976
22	APGE	Apogee Therapeutics, Inc.	1.62%	32,718
23	TARS	Tarsus Pharmaceuticals, Inc.	1.52%	27,550
24	AGIO	Agios Pharmaceuticals, Inc.	1.52%	41,683
25	GLPG	Galapagos NV	1.49%	47,644
26	IRON	Disc Medicine, Inc.	1.46%	25,135
27	IDYA	IDEAYA Biosciences, Inc.	1.39%	60,466
28	GPCR	Structure Therapeutics Inc.	1.31%	42,628
29	IMCR	Immunocore Holdings plc	1.31%	35,410
30	MNKD	MannKind Corporation	1.30%	216,928
31	VERA	Vera Therapeutics, Inc.	1.28%	45,701
32	EWTX	Edgewise Therapeutics, Inc.	1.24%	67,091
33	CLDX	Celldex Therapeutics, Inc.	1.24%	49,066
34	LQDA	Liquidia Corporation	1.21%	61,564
35	VRDN	Viridian Therapeutics, Inc.	0.99%	60,406
36	AUPH	Aurinia Pharmaceuticals Inc.	0.98%	97,098
37	NVAX	Novavax, Inc.	0.89%	112,239
38	RCUS	Arcus Biosciences, Inc.	0.83%	75,763
39	NTLA	Intellia Therapeutics, Inc.	0.81%	75,980
40	PHVS	Pharvaris N.V.	0.76%	35,995
41	PRAX	Praxis Precision Medicines, Inc.	0.70%	14,678
42	VIR	Vir Biotechnology, Inc.	0.67%	101,036
43	NUVB	Nuvation Bio Inc.	0.65%	240,852
44	MLYS	Mineralys Therapeutics, Inc.	0.64%	34,060
45	AVXL	Anavex Life Sciences Corp.	0.63%	59,170
46	AVBP	ArriVent BioPharma, Inc.	0.62%	24,729
47	IMNM	Immunome, Inc.	0.61%	61,454
48	DAWN	Day One Biopharmaceuticals, Inc.	0.59%	72,065
49	DNTH	Dianthus Therapeutics, Inc.	0.58%	23,272
50	ANAB	AnaptysBio, Inc.	0.57%	22,724

As of May 12, 2025

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