SPDR S&P BIOTECH ETF (XBI)

XBI Holdings List

As of Aug 12, 2025

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No.	Symbol	Name	% Weight	Shares
1	ALNY	Alnylam Pharmaceuticals, Inc.	3.57%	392,370
2	HALO	Halozyme Therapeutics, Inc.	2.86%	2,175,491
3	INSM	Insmed Incorporated	2.83%	1,195,671
4	INCY	Incyte Corporation	2.82%	1,701,632
5	GILD	Gilead Sciences, Inc.	2.70%	1,071,919
6	UTHR	United Therapeutics Corporation	2.67%	423,696
7	REGN	Regeneron Pharmaceuticals, Inc.	2.58%	225,882
8	ABBV	AbbVie Inc.	2.54%	611,782
9	NBIX	Neurocrine Biosciences, Inc.	2.45%	943,479
10	BMRN	BioMarin Pharmaceutical Inc.	2.44%	2,049,571
11	BBIO	BridgeBio Pharma, Inc.	2.42%	2,398,229
12	AMGN	Amgen Inc.	2.40%	401,421
13	BIIB	Biogen Inc.	2.36%	880,420
14	NTRA	Natera, Inc.	2.31%	702,539
15	MRNA	Moderna, Inc.	2.25%	4,221,677
16	EXEL	Exelixis, Inc.	2.22%	2,827,762
17	MDGL	Madrigal Pharmaceuticals, Inc.	2.19%	299,157
18	VRTX	Vertex Pharmaceuticals Incorporated	2.03%	258,977
19	EXAS	Exact Sciences Corporation	1.80%	2,104,908
20	ROIV	Roivant Sciences Ltd.	1.68%	7,201,827
21	CRSP	CRISPR Therapeutics AG	1.62%	1,393,660
22	VKTX	Viking Therapeutics, Inc.	1.54%	1,919,825
23	IONS	Ionis Pharmaceuticals, Inc.	1.51%	1,764,573
24	RNA	Avidity Biosciences, Inc.	1.48%	1,546,698
25	CYTK	Cytokinetics, Incorporated	1.44%	2,065,884

As of Aug 12, 2025

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