SPDR S&P BIOTECH ETF (XBI)

XBI Holdings List

As of Sep 25, 2025

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No.	Symbol	Name	% Weight	Shares
1	CRSP	CRISPR Therapeutics AG	2.20%	2,002,642
2	UTHR	United Therapeutics Corporation	2.04%	263,522
3	ABBV	AbbVie Inc.	1.96%	493,610
4	EXEL	Exelixis, Inc.	1.95%	2,771,341
5	MRNA	Moderna, Inc.	1.93%	4,297,769
6	REGN	Regeneron Pharmaceuticals, Inc.	1.90%	187,988
7	NBIX	Neurocrine Biosciences, Inc.	1.90%	739,691
8	IONS	Ionis Pharmaceuticals, Inc.	1.87%	1,632,503
9	MDGL	Madrigal Pharmaceuticals, Inc.	1.87%	242,930
10	VRTX	Vertex Pharmaceuticals Incorporated	1.87%	268,953
11	EXAS	Exact Sciences Corporation	1.86%	1,907,606
12	HALO	Halozyme Therapeutics, Inc.	1.86%	1,378,336
13	AMGN	Amgen Inc.	1.85%	375,141
14	BMRN	BioMarin Pharmaceutical Inc.	1.84%	1,917,023
15	NTRA	Natera, Inc.	1.83%	615,329
16	GILD	Gilead Sciences, Inc.	1.83%	906,581
17	ALNY	Alnylam Pharmaceuticals, Inc.	1.82%	222,592
18	BIIB	Biogen Inc.	1.81%	732,632
19	RVMD	Revolution Medicines, Inc.	1.81%	2,334,237
20	INCY	Incyte Corporation	1.80%	1,211,396
21	INSM	Insmed Incorporated	1.77%	715,995
22	BBIO	BridgeBio Pharma, Inc.	1.76%	1,972,849
23	TGTX	TG Therapeutics, Inc.	1.74%	2,752,539
24	RNA	Avidity Biosciences, Inc.	1.67%	2,251,777
25	ROIV	Roivant Sciences Ltd.	1.66%	6,080,452

As of Sep 25, 2025

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