SPDR S&P BIOTECH ETF (XBI)

XBI Holdings List

As of Jun 26, 2025

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No.	Symbol	Name	% Weight	Shares
1	ALNY	Alnylam Pharmaceuticals, Inc.	2.57%	399,427
2	EXEL	Exelixis, Inc.	2.51%	2,879,052
3	INSM	Insmed Incorporated	2.50%	1,217,242
4	INCY	Incyte Corporation	2.48%	1,732,486
5	UTHR	United Therapeutics Corporation	2.48%	431,455
6	NBIX	Neurocrine Biosciences, Inc.	2.46%	960,573
7	NTRA	Natera, Inc.	2.43%	715,316
8	REGN	Regeneron Pharmaceuticals, Inc.	2.42%	230,015
9	MRNA	Moderna, Inc.	2.39%	4,298,350
10	GILD	Gilead Sciences, Inc.	2.37%	1,091,323
11	VRTX	Vertex Pharmaceuticals Incorporated	2.36%	263,634
12	ABBV	AbbVie Inc.	2.35%	622,929
13	HALO	Halozyme Therapeutics, Inc.	2.35%	2,215,010
14	AMGN	Amgen Inc.	2.31%	408,750
15	BIIB	Biogen Inc.	2.30%	896,469
16	BMRN	BioMarin Pharmaceutical Inc.	2.28%	2,086,801
17	EXAS	Exact Sciences Corporation	2.24%	2,142,814
18	BBIO	BridgeBio Pharma, Inc.	2.23%	2,441,705
19	BPMC	Blueprint Medicines Corporation	1.95%	751,530
20	MDGL	Madrigal Pharmaceuticals, Inc.	1.84%	304,400
21	TGTX	TG Therapeutics, Inc.	1.79%	2,335,421
22	ROIV	Roivant Sciences Ltd.	1.72%	7,331,536
23	IONS	Ionis Pharmaceuticals, Inc.	1.44%	1,796,318
24	CYTK	Cytokinetics, Incorporated	1.44%	2,102,875
25	RVMD	Revolution Medicines, Inc.	1.44%	1,898,193
26	PCVX	Vaxcyte, Inc.	1.36%	2,045,090
27	SWTX	SpringWorks Therapeutics, Inc.	1.34%	1,414,612
28	CRSP	CRISPR Therapeutics AG	1.34%	1,418,843
29	AKRO	Akero Therapeutics, Inc.	1.31%	1,155,489
30	KRYS	Krystal Biotech, Inc.	1.24%	430,079
31	ADMA	ADMA Biologics, Inc.	1.23%	3,299,636
32	PTCT	PTC Therapeutics, Inc.	1.21%	1,211,422
33	ALKS	Alkermes plc	1.17%	2,001,052
34	PTGX	Protagonist Therapeutics, Inc.	1.12%	999,376
35	VKTX	Viking Therapeutics, Inc.	1.11%	1,954,066
36	SMMT	Summit Therapeutics Inc.	1.06%	2,467,363
37	SLNO	Soleno Therapeutics, Inc.	1.00%	588,140
38	NUVL	Nuvalent, Inc.	0.96%	600,371
39	RNA	Avidity Biosciences, Inc.	0.95%	1,574,400
40	ACLX	Arcellx, Inc.	0.92%	699,406
41	SRRK	Scholar Rock Holding Corporation	0.89%	1,239,054
42	RYTM	Rhythm Pharmaceuticals, Inc.	0.80%	640,369
43	RARE	Ultragenyx Pharmaceutical Inc.	0.76%	1,006,197
44	VCYT	Veracyte, Inc.	0.73%	1,350,231
45	BCRX	BioCryst Pharmaceuticals, Inc.	0.73%	3,734,192
46	TWST	Twist Bioscience Corporation	0.70%	938,595
47	ACAD	ACADIA Pharmaceuticals Inc.	0.70%	1,560,230
48	CRNX	Crinetics Pharmaceuticals, Inc.	0.68%	1,126,109
49	APLS	Apellis Pharmaceuticals, Inc.	0.66%	1,784,971
50	SRPT	Sarepta Therapeutics, Inc.	0.64%	1,837,013

As of Jun 26, 2025

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