Cogent Biosciences, Inc. (COGT)

NASDAQ: COGT · Real-Time Price · USD
38.77
-0.54 (-1.37%)
At close: Dec 5, 2025, 4:00 PM EST
38.51
-0.26 (-0.67%)
After-hours: Dec 5, 2025, 7:58 PM EST
-1.37%
Market Cap 5.90B
Revenue (ttm) n/a
Net Income (ttm) -294.37M
Shares Out 152.13M
EPS (ttm) -2.47
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 1,840,481
Open 39.46
Previous Close 39.31
Day's Range 38.20 - 39.94
52-Week Range 3.72 - 41.27
Beta 0.51
Analysts Buy
Price Target 28.08 (-27.57%)
Earnings Date Nov 3, 2025

About COGT

Cogent Biosciences, Inc., a biotechnology company, focuses on developing precision therapies for genetically defined diseases. Its lead product candidate includes bezuclastinib (CGT9486), a selective tyrosine kinase inhibitor in Phase 3 trial designed to target mutations within the KIT receptor tyrosine kinase, including KIT D816V mutation that drives systemic mastocytosis, as well as other mutations in KIT exon 17, which are found in patients with advanced gastrointestinal stromal tumors. The company also develops CGT4859, a reversible and sel... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Mar 29, 2018
Employees 205
Stock Exchange NASDAQ
Ticker Symbol COGT
Full Company Profile

Financial Performance

Financial Statements

Analyst Forecast

According to 13 analysts, the average rating for COGT stock is "Buy." The 12-month stock price target is $28.08, which is a decrease of -27.57% from the latest price.

Price Target
$28.08
(-27.57% downside)
Analyst Consensus: Buy
Stock Forecasts

News

Cogent Biosciences Presents Full SUMMIT Results of Bezuclastinib in Patients with NonAdvanced Systemic Mastocytosis (NonAdvSM) at the 67th Annual Meeting of the American Society of Hematology (ASH)

-- Bezuclastinib achieves clear clinical benefit across all symptom domains including significant improvements on 11 individual symptoms plus the most severe symptom at baseline -- -- Bezuclastinib de...

2 hours ago - GlobeNewsWire

3 Potential Mid-Cap Biotech Buyout Targets In 2026

The biotech sector began December with notable weakness, as both IBB and XBI ETFs declined over two percent during trading on Monday.  The sector has bounced back since. However, small biotech stocks ...

Other symbols: IBBTVTXXBICYTK
2 days ago - Seeking Alpha

Cogent Biosciences Announces Participation in the Jefferies Global Healthcare Conference

WALTHAM, Mass. and BOULDER, Colo., Nov. 14, 2025 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined ...

22 days ago - GlobeNewsWire

Cogent Biosciences Announces Pricing of Concurrent Public Offerings of Common Stock and 1.625% Convertible Senior Notes Due 2031

WALTHAM, Mass. and BOULDER, Colo., Nov. 11, 2025 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (“Cogent”) (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetical...

24 days ago - GlobeNewsWire

Cogent Biosciences: Soaring On Blowout GIST Data - I Expect More Upside

Cogent Biosciences, Inc. soared 120% after positive Phase 3 PEAK study results for bezuclastinib in imatinib-resistant GIST patients. COGT's bezuclastinib showed a 50% reduction in disease progression...

25 days ago - Seeking Alpha

Cogent: Another Win For Bezuclastinib In GIST Warrants Continued Strong Buy

Cogent Biosciences, Inc. earns a Strong Buy rating due to positive phase 3 PEAK results for bezuclastinib + Sunitinib in 2nd-line GIST. Company's combination therapy showed a significant mPFS improvem...

25 days ago - Seeking Alpha

Cogent Biosciences, Inc. (COGT) Discusses Positive Phase 3 PEAK Trial Results of Bezuclastinib in Gastrointestinal Stromal Tumors Transcript

Cogent Biosciences, Inc. ( COGT) Discusses Positive Phase 3 PEAK Trial Results of Bezuclastinib in Gastrointestinal Stromal Tumors November 10, 2025 8:00 AM EST Company Participants Christi Waarich -...

25 days ago - Seeking Alpha

Cogent Biosciences' Lead Cancer Drug Cuts Disease Progression Or Death Risk By 50% In Stomach Cancer Trial

Cogent Biosciences, Inc. (NASDAQ:COGT) stock is trading higher on Monday, with a session volume of 10.95 million compared to the average volume of 1.97 million as per data from Benzinga Pro.

26 days ago - Benzinga

Cogent Biosciences Reports Positive Results from Bezuclastinib PEAK Phase 3 Trial in Gastrointestinal Stromal Tumors (GIST)

16.5 months median progression free survival (mPFS) for bezuclastinib plus sunitinib compared to 9.2 months mPFS for sunitinib monotherapy (HR=0.50, CI: 0.39-0.65; p

26 days ago - GlobeNewsWire

Cogent Biosciences Reports Recent Business Highlights and Third Quarter 2025 Financial Results

Phase 3 PEAK results in 2 nd -line GIST patients expected in November; pivotal APEX results in AdvSM patients expected in December

4 weeks ago - GlobeNewsWire

Cogent Biosciences Announces Multiple Presentations at the 67th Annual American Society of Hematology (ASH) Meeting

SUMMIT data for bezuclastinib in NonAdvSM selected for two oral presentations which will describe its best-in-class potential Novel JAK2 V617F mutant-selective inhibitor announced as Cogent's newest p...

4 weeks ago - GlobeNewsWire

Cogent Biosciences Announces KRAS Poster Presentation at the 2025 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics

WALTHAM, Mass. and BOULDER, Colo., Oct. 24, 2025 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc.  (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined...

6 weeks ago - GlobeNewsWire

Cogent Biosciences Announces FDA Breakthrough Therapy Designation for Bezuclastinib

Detailed results from bezuclastinib's positive SUMMIT trial evaluating bezuclastinib in patients with NonAdvanced Systemic Mastocytosis planned for presentation at upcoming scientific conference this ...

6 weeks ago - GlobeNewsWire

Cogent Biosciences Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

WALTHAM, Mass. and BOULDER, Colo.

2 months ago - GlobeNewsWire

Cogent Biosciences, Inc. (COGT) Presents At Citi's Biopharma Back To School Conference Transcript

Cogent Biosciences, Inc. (NASDAQ:COGT) Citi's Biopharma Back to School Conference September 3, 2025 9:00 AM EDT Company Participants Andrew Robbins - President, CEO & Director Conference Call Partici...

3 months ago - Seeking Alpha

Cogent Biosciences Announces Participation in the Citi Biopharma Conference

WALTHAM, Mass. and BOULDER, Colo.

3 months ago - GlobeNewsWire

Cogent Biosciences Reports Recent Business Highlights and Second Quarter 2025 Financial Results

Reported positive top-line results from SUMMIT evaluating bezuclastinib in patients with NonAdvanced Systemic Mastocytosis, achieving statistical significance across all primary and key secondary endp...

4 months ago - GlobeNewsWire

Cogent Biosciences Announces Closing of Upsized Public Offering of Shares of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares

WALTHAM, Mass. and BOULDER, Colo., July 10, 2025 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined ...

5 months ago - GlobeNewsWire

Cogent: Positive Data In NonAdvSM Bodes Well For 2nd Half AdvSM Treatment Results

I have upgraded Cogent Biosciences, Inc. to Strong Buy after positive SUMMIT trial data for bezuclastinib in non-advanced systemic mastocytosis patients. COGT plans to submit an NDA for bezuclastinib ...

5 months ago - Seeking Alpha

Cogent Biosciences Announces Pricing of Upsized Public Offering of Shares of Common Stock

WALTHAM, Mass. and BOULDER, Colo., July 08, 2025 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined ...

5 months ago - GlobeNewsWire

Cogent Biosciences Announces Proposed $150 Million Public Offering of Common Stock

WALTHAM, Mass. and BOULDER, Colo., July 08, 2025 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined ...

5 months ago - GlobeNewsWire

Why Is Cogent Biosciences Stock Trading Higher On Monday?

Cogent Biosciences, Inc.‘s  COGT bezuclastinib showed meaningful clinical benefit for patients with non-advanced systemic mastocytosis, a rare and debilitating immune disorder.

5 months ago - Benzinga

Cogent Biosciences Announces Positive Top-line Results Achieving Statistical Significance Across All Primary and Key Secondary Endpoints from the SUMMIT Trial of Bezuclastinib in Patients with Non-Advanced Systemic Mastocytosis

-- Patients treated with bezuclastinib showed a superior mean change in total symptom score at 24 weeks (-24.3 points vs. -15.4 points, -8.91 point placebo-adjusted difference; p=0.0002), compared to ...

5 months ago - GlobeNewsWire

Cogent Biosciences Secures up to $400 Million in Non-Dilutive Financing

Facility provides additional funding for next steps of the Company's growth, including the expected launch of bezuclastinib in 2026 On track to report results from three pivotal trials this year, begi...

6 months ago - GlobeNewsWire