Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
33.45
-0.06 (-0.18%)
Dec 5, 2025, 4:00 PM EST - Market closed
Spyre Therapeutics Analyst Ratings
Total Analysts
4
Consensus Rating
Strong Buy
Price Target
$55.50
Upside
+65.92%
Ratings History
| Analyst | Firm | Rating | Rating | Action | Price Target | Upside | Date |
|---|---|---|---|---|---|---|---|
| Jones Trading | Jones Trading | Hold → Strong Buy Upgrades $64 | Hold → Strong Buy | Upgrades | $64 | +91.33% | Dec 1, 2025 |
| Deutsche Bank | Deutsche Bank | Strong Buy Initiates $43 | Strong Buy | Initiates | $43 | +28.55% | Sep 26, 2025 |
| BTIG | BTIG | Strong Buy Reiterates $70 | Strong Buy | Reiterates | $70 | +109.27% | Sep 16, 2025 |
| Leerink Partners | Leerink Partners | Buy Initiates $45 | Buy | Initiates | $45 | +34.53% | Apr 8, 2025 |
| Jones Trading | Jones Trading | Hold Initiates n/a | Hold | Initiates | n/a | n/a | Dec 11, 2024 |
| Baird | Baird | Buy Maintains $50 → $65 | Buy | Maintains | $50 → $65 | +94.32% | Nov 13, 2024 |
| Guggenheim | Guggenheim | Strong Buy Maintains $50 → $65 | Strong Buy | Maintains | $50 → $65 | +94.32% | Oct 25, 2024 |
| Wedbush | Wedbush | Buy Initiates $45 | Buy | Initiates | $45 | +34.53% | Sep 4, 2024 |
| Evercore ISI Group | Evercore ISI Group | Buy Initiates n/a | Buy | Initiates | n/a | n/a | Jul 16, 2024 |
| Wells Fargo | Wells Fargo | Buy Maintains $35 → $40 | Buy | Maintains | $35 → $40 | +19.58% | May 13, 2024 |
| BTIG | BTIG | Strong Buy Maintains $32 → $40 | Strong Buy | Maintains | $32 → $40 | +19.58% | May 10, 2024 |
| Baird | Baird | Buy Initiates $50 | Buy | Initiates | $50 | +49.48% | May 2, 2024 |
| Stifel | Stifel | Strong Buy Reiterates $36 → $54 | Strong Buy | Reiterates | $36 → $54 | +61.43% | Mar 26, 2024 |
| Wells Fargo | Wells Fargo | Hold → Buy Upgrades $12 → $35 | Hold → Buy | Upgrades | $12 → $35 | +4.63% | Mar 1, 2024 |
| BTIG | BTIG | Strong Buy Initiates $32 | Strong Buy | Initiates | $32 | -4.33% | Dec 20, 2023 |
| Stifel | Stifel | Strong Buy Maintains $23 → $27 | Strong Buy | Maintains | $23 → $27 | -19.28% | Dec 18, 2023 |
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Analyst Star Rankings
Our analyst star rankings are based on these four factors
- Success Rate
- The percentage of ratings that are profitable.
- Average Return
- The average percentage return within one year of the rating.
- Rating Count
- The more ratings the analyst has provided, the higher the score.
- Recency
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