Upstream Bio, Inc. (UPB)
NASDAQ: UPB · Real-Time Price · USD
27.75
+0.01 (0.04%)
At close: Dec 5, 2025, 4:00 PM EST
28.30
+0.55 (1.98%)
After-hours: Dec 5, 2025, 7:47 PM EST

Company Description

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders.

Its product candidate includes verekitug, which is in Phase 2 clinical development for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps, as well as in Phase I clinical trial for treating chronic obstructive pulmonary disease.

The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.

Upstream Bio, Inc.
Upstream Bio logo
Country United States
Founded 2021
IPO Date Oct 11, 2024
Industry Biotechnology
Sector Healthcare
Employees 52
CEO E. Sutherland

Contact Details

Address:
890 Winter Street, Suite 200
Waltham, Massachusetts 02451
United States
Phone 781 208 2466
Website upstreambio.com

Stock Details

Ticker Symbol UPB
Exchange NASDAQ
Fiscal Year January - December
Reporting Currency USD
IPO Price $17.00
CIK Code 0002022626
ISIN Number US91678A1079
SIC Code 2834

Key Executives

Name Position
Dr. E. Rand Sutherland M.D., M.P.H., MPH Chief Executive Officer and Director
Michael Paul Gray CPA, MBA Chief Financial Officer and Chief Operating Officer
Allison C. Ambrose J.D. Senior Vice President, General Counsel and Secretary
Stacy Price M.S., P.M.P. Chief Technology Officer
Meggan Buckwell Director of Corporate Communications and Investor Relations
Lisa Fiering Senior Vice President of People and Culture
Dr. Adam Houghton M.B.A., Ph.D. Chief Business Officer
Aaron Deykin M.D. Chief Medical Officer and Head of Research and Development
Mersedeh Miraliakbari Pharm.D. Senior Vice President of Regulatory Affairs and Quality
Fang Xie Ph.D. Vice President and Head of Biometrics

Latest SEC Filings

Date Type Title
Nov 14, 2025 SCHEDULE 13G/A Filing
Nov 14, 2025 SCHEDULE 13G/A Filing
Nov 5, 2025 S-3ASR Automatic shelf registration statement of securities of well-known seasoned issuers
Nov 5, 2025 10-Q Quarterly Report
Nov 5, 2025 8-K Current Report
Oct 24, 2025 SCHEDULE 13G Filing
Sep 2, 2025 8-K Current Report
Aug 6, 2025 SCHEDULE 13G/A Filing
Aug 6, 2025 10-Q Quarterly Report
Aug 6, 2025 8-K Current Report