Upstream Bio, Inc. (UPB)

NASDAQ: UPB · Real-Time Price · USD

27.75

+0.01 (0.04%)

At close: Dec 5, 2025, 4:00 PM EST

28.30

+0.55 (1.98%)

After-hours: Dec 5, 2025, 7:47 PM EST

Upstream Bio Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022
Period Ending	Dec '25 Dec 5, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022
Market Capitalization	1,500	881	-	-
Enterprise Value	1,129	1,043	-	-
Last Close Price	27.75	16.44	-	-
PS Ratio	535.75	371.78	-	-
PB Ratio	3.96	1.88	-	-
P/TBV Ratio	3.96	1.88	-	-
EV/Sales Ratio	403.20	440.20	-	-
Debt / Equity Ratio	0.00	0.00	0	0.01
Asset Turnover	0.01	0.01	0.04	-
Quick Ratio	31.47	43.93	16.89	3.60
Current Ratio	32.67	44.63	17.96	3.77
Return on Equity (ROE)	-40.80%	-21.75%	-35.88%	-
Return on Assets (ROA)	-28.15%	-16.23%	-36.96%	-
Return on Capital (ROIC)	-29.15%	-16.77%	-43.75%	-
Return on Capital Employed (ROCE)	-37.00%	-16.50%	-36.20%	-175.50%
Earnings Yield	-9.06%	-7.13%	-	-
FCF Yield	-8.17%	-6.77%	-	-
Buyback Yield / Dilution	-1624.00%	-363.22%	-5.49%	-

Updated Nov 5, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q